Endothelial ATP-Sensitive Potassium Channel Protects Against the Development of Hypertension and Atherosclerosis
نویسندگان
چکیده
منابع مشابه
A new ATP-sensitive potassium channel opener protects endothelial function in cultured aortic endothelial cells.
OBJECTIVE Endothelial dysfunction is an early risk factor for cardiovascular disease and hypertension. Mechanisms that participate in endothelial dysfunction include reduced nitric oxide (NO) generation and increased endothelin-1 (ET-1) generation. Endothelial ATP-sensitive potassium (K(ATP)) channels are responsible for maintaining the resting potential of endothelial cells and modulating the ...
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ژورنال
عنوان ژورنال: Hypertension
سال: 2020
ISSN: 0194-911X,1524-4563
DOI: 10.1161/hypertensionaha.120.15355